1. Signaling Pathways
  2. GPCR/G Protein
    Neuronal Signaling
  3. Neurokinin Receptor
  4. Neurokinin Receptor Agonist

Neurokinin Receptor Agonist

Neurokinin Receptor Agonists (30):

Cat. No. Product Name Effect Purity
  • HY-P0187
    Senktide
    Agonist 99.72%
    Senktide is a tachykinin NK3 receptor agonist.
  • HY-P10599
    Scyliorhinin I
    Agonist
    Scyliorhinin I is a tachykinin-1 (NK-1) and tachykinin-2 (NK-2) receptor agonist with a Ki value of 0.9 nM for rat submandibular gland NK-1 receptor and 2 nM for hamster bladder NK-2 receptor. Scyliorhinin I has the ability to contract the longitudinal muscles of the guinea pig ileum.
  • HY-P0242A
    Neurokinin B TFA
    Agonist 98.59%
    Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.
  • HY-P0236A
    Neurokinin A(4-10) TFA
    Agonist 98.84%
    Neurokinin A (4-10) TFA is a tachykinin NK2 receptor agonist.
  • HY-P1198
    Hemokinin 1, human
    Agonist 98.11%
    Hemokinin 1, human is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human can produces an opioid-independent analgesia.
  • HY-P1012
    [Sar9,Met(O2)11]-Substance P
    Agonist 98.84%
    [Sar9,Met(O2)11]-Substance P is a tachykinin NK1 receptor selective agonist.
  • HY-P1030
    Hemokinin 1 (mouse)
    Agonist 99.49%
    Hemokinin 1 (mouse) is a selective agonist of neurokinin-1 receptor, with Ki of 0.175 nM and 560 nM for human NK1 receptor and human NK2 receptor, respectively.
  • HY-P1031
    [bAla8]-Neurokinin A(4-10)
    Agonist
    [bAla8]-Neurokinin A(4-10) is a neurokinin 2 (NK2) receptor agonist.
  • HY-P3849
    [Lys5,MeLeu9,Nle10]Neurokinin A(4-10)
    Agonist 99.83%
    [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) (LMN-NKA), an analogue of Neurokinin A, is a selective and potent NK2R agonist. [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) has prokinetic activity. [Lys5,MeLeu9,Nle10]Neurokinin A(4-10) can be used to study the roles of the NK-2 receptor in smooth muscle contraction in numerous tissues.
  • HY-P1738
    [Sar9] Substance P
    Agonist 98.14%
    [Sar9] Substance P is a potent and selective neurokinin (NK)-1 receptor agonist.
  • HY-P1012A
    [Sar9,Met(O2)11]-Substance P TFA
    Agonist 98.58%
    [Sar9,Met(O2)11]-Substance P TFA is a tachykinin NK1 receptor selective agonist.
  • HY-P1192
    GR-73632
    Agonist 99.93%
    GR-73632 is a novel tachykinin neurokinin 1 (NK-1) receptor agonist. GR-73632 acts directly on the peripheral terminals of primary sensory neurons through NK1 receptor which convey itch signals.
  • HY-P3069
    γ-Neuropeptide (rabbit)
    Agonist
    γ-Neuropeptide (rabbit) can be isolated from rabbit intestine. γ-Neuropeptide is an endogenous neurokinin peptide that acts as a neurokinin 2 (NK2) receptor agonist. γ-Neuropeptide mediates hypothalamic-pituitary-adrenal (HPA) axis, as well as reproductive hormone release.
  • HY-P2000
    Septide
    Agonist 98.97%
    Septide ((Pyr6,Pro9)-Substance P) is a potent NK1 receptor agonist with a Kd value of 0.55 nM.
  • HY-P0242
    Neurokinin B
    Agonist
    Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.
  • HY-P1198A
    Hemokinin 1, human TFA
    Agonist
    Hemokinin 1, human TFA is a selective tachykinin neurokinin 1 (NK1) receptor full agonist. Hemokinin 1, human TFA is a full agonist at NK2 and NK3 receptor. Hemokinin 1, human TFA can produces an opioid-independent analgesia.
  • HY-P3092
    Phyllomedusin
    Agonist
    Phyllomedusin, an tachykinin decapeptide, is a NK1 receptor agonist. Phyllomedusin has vasodilating activity and provokes the contraction of the pylorus.
  • HY-P1506
    [Nle11]-Substance P
    Agonist
    [Nle11]-Substance P is a substance P analog that avoids methionine oxidation problems.
  • HY-P10746
    EB1002
    Agonist
    EB1002 is a selective NK2R agonist. EB1002 significantly raises the expression levels of mitochondrial biosynthesis-related genes (like PGC-1α) in obese mice, indicating that it promotes energy expenditure by boosting mitochondrial activity. EB1002 also increases the insulin sensitivity and improves glycolipid metabolism of the mice. EB1002 is promising for research of obesity and type 2 diabetes.
  • HY-P1588
    Scyliorhinin II
    Agonist
    Scyliorhinin II is a selective neurokinin-3 receptor agonist, with a Ki of 2.5 nM for neurokinin-3 receptor in rat cerebral cortex.